Wound Repair and Regeneration published by Wiley Periodicals, Inc. There are ongoing discussions regarding the intensity, intermittent or constant pressure, and the filler material to cover the wound. Providers should consider targeting therapy to those patients at elevated risk of surgical site complications to maximize efficiency. In conclusion, single-use negative pressure wound therapy can be considered a cost saving intervention to reduce surgical site complications following primary hip and knee replacements compared with standard care. The findings were robust to a range of sensitivity analyses. Greater savings were observed in subgroups of higher risk patients with BMI ≥ 35 and ASA ≥ 3 i.e., £7,955 ($11,296) and £7,248 ($10,293), respectively. It relies on generating a negative pressure on the surface of the wound, which is believed to promote wound healing. The cost/patient was £5,602 ($7,954) and £6,713 ($9,559) for single-use negative pressure wound therapy and standard care respectively resulting in cost-saving of £1,132 ($1,607) in favor of single-use negative pressure wound therapy. Negative-pressure wound therapy (NPWT) is being increasingly used in the management of different types of wounds over the last few decades. 1 Negative pressure wound therapy (NPWT) has been a revolutionary tool in advancing wound healing. The model estimated 0.116 and 0.115 QALY gained, 0.98 and 0.92 complications avoided for single-use negative pressure wound therapy and standard care, respectively. One evaluation estimates that wound care health expenditures are between 28.1 billion and 96.8 billion for the US Medicare population alone. The randomized controlled trial reported a reduction in dressing changes (p = 0.002), SSC (p = 0.06) and LOS (p = 0.07) in favor of single-use negative pressure wound therapy compared with standard care. Outcomes included dressing changes, length of stay, surgical site complications, cost and quality adjusted life years. 220 patients were randomized to treatment with either single-use negative pressure wound therapy or standard care i.e., film dressings of clinician choice and followed for 6 weeks. The large market share of this segment is attributed to the increased prevalence of diabetes-associated wounds, heightened awareness regarding diabetic foot ulcers and their associated. A decision analytic model was developed from UK National Health Service perspective using data from a single-centre trial. Negative Pressure Wound Therapy, also known as Vacuum Assisted Closure (V.A.C.), is a new treatment in which controlled negative pressure is used to provide evacuation of wound fluid, stimulation of granulation tissue, and a decrease in bacterial colonization. We sought to evaluate the cost-effectiveness of single-use negative pressure wound therapy in patients undergoing primary hip and knee replacements using effectiveness data from a recently completed non-blinded randomized controlled trial.
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